Team Dicty: Environmental Molecular Biology Lab

- Department of Materials and Life Sciences, Faculty of Science and Engineering, Sophia University
- Graduate School of Science and Engineering, Sophia University

Welcome to Team Dicty official website!
We are studying Chemical Ecology and Chemical Biology using a model organism, Cellular Slime Mold.

日本語/English
Last Updated: 12 August 2024
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Information

2024-04-01
The spring semester of 2024 has begun.
Three new members (three B4 students) joined Team Dicty!
2024-03-25
Graduation ceremony March 2024. T Five students in Master course and five in Bachelor's program graduated from Team Dicty. Congratulations!!
2023-11-01
Ms. S. Nezu, Ms. R. Suzuki and S. Fuchimoto presented their works in the 96th Annual Meeting of the Japanese Biochemical Society (Fukuoka Congress Centre).
2023-10-21
Ms. K. Hayashi presented her work in the 2023 Annual Meeting of Japanese Society for the Study of Cellular Slime Mold (Kyushu Institute of Technology).
2023-09-21
The fall semester of 2023 has begun.
One new members (B4: Green Science Course) joined Team Dicty!
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Research

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Introduction

Dicty RRK photo

Natural products are the major source of therapeutic small molecules; not just for anti-bacterials and anti-fungals but also for anti-cancers where around half of existing drugs have this origin.
Dictyostelium is a social amoebae living in a soil, where is known as a battle field of chemical warfare. Dicty genome analysis revealed its massive potential of the production of small molecules, secondary metabolites.
What do these chemical compounds do in the soil?

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Chemical Ecology

nematode_infection

Understand the chemical communication between Dicty and plant-parasitic nematode to invent a novel Pest Management strategy for sustainable agriculture.

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Chemical Biology

Steely enzymes

Understand the biosynthetic mechanism and biological function of halogenated dibenzofurans produced in Dictyostelium fruiting body.

Reference books
  • Paul G. Falkowski "Life's Engines: How Microbes Made Earth Habitable" Princeton Univ Press 2015
  • Richard H. Kessin “DICTYOSTELIUM” Cambridge University Press 2001

Link

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