TEL. +81-3-3238-3089

E-mail yumiko_suzuki[at]sophia.ac.jp

Sophia University, 7-1 Kioicho, Chiyoda-ku, Tokyo 102-8554, Japan

Publications
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  • Sophia University
    1. Christian Nanga Chick, Tomoyo Misawa-Suzuki, Yumiko Suzuki, Toyonobu Usuki:
      "Preparation and antioxidant study of silver-nanoparticles of Microsorum pteropus methanol extract."
      Bioorg. Med. Chem. Lett., 2020, 30, 127526.
    2. Yumiko Suzuki, Ayana Otake, Satoshi Ueno, Kensuke Hayashi, Hirosuke Ishii, Nao Miyoshi, Kenta Kuroiwa, Masashi Tachikawa, Yuki Fujimaki, Kotaro Nishiyama, Akira Asai, Kei Manabe, Ryuta Yamazaki:
      "Discovery of a Potent Anticancer Agent PVHD303 with In Vivo Activity."
      ACS Med. Chem. Lett., 2020, 11, 1287-1291.
    3. Kazusa Aoki, Ryuji Osako, Jiahui Deng, Takashi Hayashita, Takeshi Hashimoto, Yumiko Suzuki:
      "Phosphate-sensing with (di-(2-picolyl)amino)quinazolines based on fluorescence on-off system."
      RSC Adv., 2020, 10, 15299-15306.
    4. Kenta Hagiwara, Hiroshi Uchida, Yumiko Suzuki, Takashi Hayashita, Kenjiro Torigoe, Tetsuya Kida, Satoshi Horikoshi:
      "Role of alkan-1-ol solvents in the synthesis of yellow luminescent carbon quantum dots (CQDs): Van der Waals force-caused aggregation and agglomeration."
      RSC Adv., 2020, 10, 14396-14402.
    5. Jun-ichi Sawada, Hirosuke Ishii, Kenji Matsuno, Masayuki Sato, Yumiko Suzuki, Akira Asai:
      “Selective inhibition of spindle microtubules by a tubulin-binding quinazoline derivative.”
      Mol. Pharmacol, 2019, 96, 609–618.
    6. Saki Ito, Taiki Kitamura, Sundaram Arulmozhiraja, Kei Manabe, Hiroaki Tokiwa,Yumiko Suzuki:
      Total Synthesis of Termicalcicolanone A via Organocatalysis and Regioselective Claisen Rearrangement.
      Organic Letters, 2019, 21, 2777-2781.
      (doi:10.1021/acs.orglett.9b00731)
    7. Yumiko Suzuki, Asuka Ando, Mizuki Nakagawa:
      Synthesis of 4-acylcoumarins by NHC-catalyzed nucleophilic substitution
      Tetrahedron Letters 2018, 59, 4276-4278. (doi:10.1016/j.tetlet.2018.10.044)
    8. Ryo Takashima, Maki Shinozaki, Kaoru Tsunekawa, Yumiko Suzuki:
      Selective Synthesis of 1,4,5-Trisubstituted Imidazoles from alpha-Imino Ketones Prepared by N-Heterocyclic Carbene-Catalyzed Aroylation
      Tetrahedron 2018, 74, 2261-2267. (doi:10.1016/j.tet.2018.03.048)
    9. Yumiko Suzuki:
      Asymmetric Michael Addition Mediated by Chiral Ionic Liquids
      Mini-Reviews in Organic Chemistry 2018, 15, 236-245. (doi:10.2174/1570193X15666171211165344)
    10. Satoshi Hirikoshi, Tomoki Watanabe, Atsushi Narita, Yumiko Suzuki, Nick Serpone:
      The electromagnetic wave energy effect(s) in microwave-assisted organic syntheses (MAOS)
      Scientific Reports 2018, 8, 5151. (doi:10.1038/s41598-018-23465-5)
    11. Masashi Tachikawa, Mizuki Nakagawa, Yumiko Suzuki:
      Nucleophilic Aroylation on Fluoroquinazolines Catalyzed by N-Heterocyclic Carbenes
      Heterocycles 2018, 96, 716-732. (doi:10.3987/COM-18-13880)
    12. Yumiko Suzuki, Naoto Iwata, Kohei Dobashi, Ryo Takashima, Sundaram Arulmozhiraja, Erika Ishitsubo, Naoya Matsuo, Hiroaki Tokiwa:
      Alkanoylation of quinazoline by nucleophilic aromatic substitution: Combined experimental and computational study
      Tetrahedron 2018, 74, 392-400. (doi:10.1016/j.tet.2017.11.071)
    13. Yumiko Suzuki, Jun-ichi Sawada, Paulina Hibner, Hirosuke Ishii, Kenji Matsuno, Masayuki Sato, Bernhard Witulski, Akira Asai:
      Fluorescent anticancer quinazolines as molecular probes for β-tubulin colchicine site competition assay and visualization of microtubules as intracellular targeting sites
      Dyes and Pigments 2017, 145, 233-238. (doi:10.1016/j.dyepig.2017.05.050)
    14. Satoshi Horikoshi, Tomoki Watanabe, Monoko Kamata, Yumiko Suzuki, Nick Serpone:
      Microwave-assisted organic syntheses: microwave effect on intramolecular reactios - the Claisen rearrangement of allylphenyl ether and 1-allyloxy-4-methoxybenzene
      RSC Advances 2015, 5, 90272-90280. (doi:10.1039/c5ra18039b)
    15. Kenta Kuroiwa, Hirosuke Ishii, Kenji Matsuno, Akira Asai, Yumiko Suzuki:
      Synthesis and Structure−Activity Relationship Study of 1‑Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents
      ACS Med. Chem. Lett. 2015, 6, 287-291. (doi:10.1021/ml5004684)
    16. Yumiko Suzuki, Junichiro Wakatsuki, Mariko Tsubaki, Masayuki Sato:
      Imidazolium-based chiral ionic liquids: Synthesis and application
      Tetrahedron 2013, 69, 9690-9700. (doi: 10.1016/j.tet.2013.09.017.)
    17. Yumiko Suzuki, Mai Murofushi, Kei Manabe:
      One-pot synthesis of unsymmetrical benzils and N-heteroarenes through nucleophilic aroylation catalyzed by N-heterocyclic carbene.
      Tetrahedron 2013, 69, 470-473.
  • University of Shizuoka
    1. Yumiko Suzuki, Abu Bakar Md., Takashi Tanoi, Naoko Nomura, and Masayuki Sato:
      Synthesis of unsymmetrical benzils using N-heterocyclic carbine catalysis.
      Tetrahedron 2011, 67, 4710-4715.
    2. Yumiko Suzuki, Yoshinori Fukuta, Shinya Ota, Masayo Kamiya, and Masayuki Sato:
      Xanthone natural products via N-heterocyclic carbene catalysis: Total synthesis of atroviridin.
      J. Org. Chem. 2011, 76, 3960-3967.
    3. Hirokazu Matsunaga, Kiyoshi Ikeda, Ken-ichi Iwamoto, Yumiko Suzuki, Masayuki Sato:
      A one-pot synthesis of 3-arylglutaric anhydrides by reaction of ketene with aromatic aldehydes and ketones.
      Tetrahedron Lett. 2009, 50, 2334-2336.
    4. Abu Bakar Md., Yumiko Suzuki, Masayuki Sato:
      Rh-N-heterocyclic carbene (NHC) complex-catalyzed addition of phenylboronic acid to N-sulfonyl and N-phosphinoyl aldimines.
      Chem. Pharm. Bull. 2008, 56, 973-976.
    5. Yumiko Suzuki, Shinya Ota, Yoshinori Fukuta, Yuki Ueda, Masayuki Sato:
      N-heterocyclic carbene-catalyzed nucleophilic aroylation of fluorobenzenes.
      J. Org. Chem. 2008, 73, 2420-2423.
    6. Kie Suwa, Yasuko Morie, Yumiko Suzuki, Kiyoshi Ikeda, Masayuki Sato:
      A highly efficient total synthesis of (R)-(+)-muscopyridine by intramolecular [4+2] cycloaddition of bisketene.
      Tetrahedron Lett. 2008, 49, 1510-1513.
    7. Yumiko Suzuki:
      Development of C-C bond formation and asymmetric reactions catalyzed by N-heterocyclic carbenes.
      YAKUGAKU ZASSHI 2008, 128, 1179-1185.
    8. Yumiko Suzuki:
      New developments in the N-heterocyclic carbene chemistry: Application as organocatalysts.
      J. Synth. Org. Chem. 2008, 66, 377-386.
    9. Abu Bakar Md., Yumiko Suzuki, Masayuki Sato:
      N-heterocyclic carbene ligands in copper-catalyzed addition of diethylzinc to N-sulfonylimines.
      Chem. Pharm. Bull. 2008, 56, 57-59.
    10. Yumiko Suzuki, Tomonori Toyota, Akira Miyashita, Masayuki Sato:
      Synthesis of heterocyclic compounds via nucleophilic aroylation catalyzed by imidazolidenyl carbene.
      Chem. Pharm. Bull. 2006, 54, 1653-1658.
    11. Ken-ichi Iwamoto, Masako Hamaya, Naoki Hashimoto, Hitomi Kimura, Yumiko Suzuki, Masayuki Sato:
      Benzoin reaction in water as an aqueous medium catalyzed by benzimidazolium salt.
      Tetrahedron Lett. 2006, 47, 7175-7177.
    12. Yumiko Suzuki, Abu Bakar Md., Kazuyuki Muramatsu, Masayuki Sato:
      Cyanosilylation of aldehydes catalyzed by N-heterocyclic carbenes.
      Tetrahedron 2006, 62, 4227-4231.
    13. Yumiko Suzuki, Kazuyuki Muramatsu, Kaori Yamauchi, Yasuko Morie, Masayuki Sato:
      Chiral N-heterocyclic carbenes as asymmetric acylation catalysts.
      Tetrahedron 2006, 62, 302-310.
    14. Yasuko Morie, Yumiko Suzuki, Kiyoshi Ikeda, Masayuki Sato:
      Synthesis of 2-pyrones bridged at the 3- and 6-positions by ring-closing methathesis.
      Heterocycles 2005, 65, 1167-1176.
    15. Yumiko Suzuki, Masayuki Sato:
      A facile one-pot synthesis of a-fluoro-a,a-unsaturated esters from alkoxycarbonylmethyltriphenylphosphonium bromides.
      Tetrahedron Lett. 2004, 45, 1679-1681.
    16. Yumiko Suzuki, Kaori Yamauchi, Kazuyuki Muramatsu, and Masayuki Sato:
      First example of chiral N-heterocyclic carbenes as catalysts for kinetic resolution.
      Chem. Commun. 2004, 2770-2771.
    17. Yumiko Suzuki, Tomonori Toyota, Fumie Imada, Masayuki Sato, and Akira Miyashita:
      Nucleophilic acylation of arylfluorides catalyzed by imidazolidenyl carbene.
      Chem. Commun. 2003, 1314-1315.
    18. Akira Miyashita, Yumiko Suzuki, Ken-ichi Iwamoto, Estuo Oishi, and Takeo Higashino:
      Catalytic action of azolium salts: Part X. Synthesis of 2-aroylquinoxalines,1-aroylphthal-azines, and 4-aroylcinnolines; An aroylation method using arenecarbaldehydes catalyzed by azolium salt.
      Heterocycles1998, 49, 405-413.
    19. Akira Miyashita, Yumiko Suzuki, Ken-ichi Iwamoto, and Takeo Higashino:
      Catalytic action of azolium salts: Part IX. Synthesis of 6-aroyl-9H-purines and their analogues by nucleophilic aroylation catalyzed by imidazolium or benzimidazolium salt.
      Chem. Pharm. Bull. 1998, 46, 390-399.
    20. Yumiko Suzuki, Yuki Takemura, Ken-ichi Iwamoto, Takeo Higashino, and Akira Miyashita:
      Carbon-carbon bond cleavage of a-hydroxybenzylheteroarenes catalyzed by cyanide ion; Retro-benzoin condensation affords ketones and heteroarenes and benzyl migration affords benzylheteroarenes and arenecarbaldehydes.
      Chem. Pharm. Bull. 1998, 46, 199-206.
    21. Akira Miyashita, Yumiko Suzuki, Yoko Okumura, Ken-ichi Iwamoto, and Takeo Higashino:
      Carbon-carbon bond cleavage ofa-substituted benzoins by retro-benzoin condensation: A new method of synthesizing ketones.
      Chem. Pharm. Bull. 1998, 46, 6-11.
    22. Izuru Nagasaki, Yumiko Suzuki, Ken-ichi Iwamoto, Takeo Higashino, Akira Miyashita:
      Synthesis of heteroarenecarbonitriles by electrophilic cyanation; Reaction of metalated heteroarenes with p-toluenesulfonyl cyanide.
      Heterocycles 1997, 46, 443-450.
    23. Akira Miyashita, Yumiko Suzuki, Kiyono Ohta, Ken-ichi Iwamoto, Takeo Higashino:
      Several appoaches to cyanide ion-catalyzed synthesis of 4-aroyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidines.
      Heterocycles 1998, 47, 407-414.
    24. Akira Miyashita, Kazuhiro Obae, Yumiko Suzuki, Estuo Oishi, Ken-ichi Iwamoto, and Takeo Higashino:
      Aroylation of fused pyrimidines; Synthesis of 4-aroylfuro[2,3-d]-, 4-aroylthieno[2,3-d]-,and 4-aroylisoxazolo[5,4-d]pyrimidines.
      Heterocycles 1997, 45, 2159-2173.
    25. Ken-ichi Iwamoto, Etsuo Oishi, Tomonobu Sano, Ayako Tsuchiya, Yumiko Suzuki, Takeo Higashino, Akira Miyashita:
      Ring transformation of fused pyridazines. VI. Construction of3-(2-pyridyl)indole skeleton by means of N-N bond cleavage reaction of fused pyridazines with ynamines.
      Heterocycles 1997, 45, 1551-1557.
    26. Akira Miyashita, Atsushi Numata, Yumiko Suzuki, Ken-ichi Iwamoto, Takeo Higashino:
      Olefininsertion reaction between the carbonyls of benzils; Formation of 1,4-diketones by Michael addi­tion catalyzed by cyanide ion.
      Chem. Lett. 1997, 697-698.
    27. Akira Miyashita, Yoshiyuki Matsuoka, Yumiko Suzuki, Ken-ichi Iwamoto, Takeo Higashino:
      A new method of synthesizing deoxybenzoins from 1,3-dimethyl-2-(a-benzyl-oxybenzy)imidazolium and 1,3-dimethyl-2-(a-benzyloxybenzyl)benzimidazolium iodides based on Wittig-type rearrangement.
      Chem. Pharm. Bull. 1997, 1235-1242.
    28. Akira Miyashita, Yumiko Suzuki, Izuru Nagasaki, Chie Ishiguro, Ken-ichi Iwamoto, and Takeo Higashino:
      Catalytic Action of Azolium Salts. VIII. Oxidative aroylation with arenecarbaldehydes catalyzed by 1,3-dimethylbenzimidazolium iodide.
      Chem. Pharm. Bull. 1997, 45, 1254-1258.
    29. Akira Miyashita, Izuru Nagasaki, Akiko Kawano, Yumiko Suzuki, Ken-ichi Iwamoto, Takeo Higashino:
      Electrophilic cyanations.1. Synthesis of thiocyanatoheteroarenes and tosylheteroarenes from mercapthoheteroarenes using p-toluenesulfonyl cyanide.
      Heterocycles 1997, 45, 745-755.
    30. Akira Miyashita, Yumiko Suzuki, Yuki Takemura, Ken-ichi Iwamoto, Takeo Higashino:
      Carbon-carbon bond cleavage of a-hydroxybenzylheteroarenes to ketones and heteroarenes by catalytic action of cyanide ion based on retrobenzoin condensation. Heterocycles1997, 45, 1-5.
    31. Akira Miyashita, Akihito Kurachi, Yoshiyuki Matsuoka, Noriko Tanabe, Yumiko Suzuki, Ken-ichi Iwamoto, and Takeo Higashino:
      Synthesis and reactivities of 1,3-dimethyl-2-(a-hydroxybenzyl)-imidazolium and 1,3-dimethyl-2-(a-hydroxybenzyl)benzimidazolium iodides.
      Heterocycles1997, 44, 417-426.
    32. Akira Miyashita, Yumiko Suzuki, Motoi Kobayashi, Naomi Kuriyama, and Takeo Higashino:
      Azolium salts as effective catalysts for benzoin condensation and related reactions.
      Heterocycles 1996, 43, 509-512.
    33. Akira Miyashita, Yumiko Suzuki, Yoko Okumura, Takeo Higashino:
      Synthesis of ketones by retro-benzoin condensation catalyzed by potassium cyanide.
      Chem. Pharm. Bull. 1996, 44, 252-254.
    34. Akira Miyashita, Yumiko Suzuki, Kiyono Ohta, Takeo Higashino:
      Preparation of heteroarenecarbonitriles by reaction of haloheteroarenes with potassium cyanide catalyzed by sodiump-toluenesulfinate.
      Heterocycles 1994, 39, 345-356.
    35. Akira Miyashita, Yumiko Suzuki, Ken-ichi Iwamoto, and Takeo Higashino:
      Catalytic action of azolium salts. VI. Preparation of benzoins and acyloins by condensation of aldehydes catalyzed by azolium salts.
      Chem. Pharm. Bull. 1994, 42, 2633-2635.
    36. Akira Miyashita, Hideaki Matsuda, Yumiko Suzuki, Ken-ichi Iwamoto, and Takeo Higashino:
      Catalytic action of azolium salts. IV. Preparations of 4-aroylquinazolines and 4-aroyl-1H-pyrazolo-[3,4-d]pyrimidines by catalytic action of 1,3-dimethylimidazolium iodide.
      Chem. Pharm. Bull. 1994, 44, 2017-1022.
  • Patent
    1. Akira Asai, Junichi Sawada, Kenji Matsuno, Yumiko Suzuki (Japanese Patent 2010-046911)
  • Other Publications
    1. Yumiko Suzuki
      β-Carbon Activation of Aliphatic Carbonyl Compounds
      KAGAKU 2014, Vol. 69, 72-73.
    2. 《Newspaper Article》
      とうきょう便ウィークリー (Japanese, PDF 358KB)
      Shizuoka Shimbun (2013/7/22)
    3. Yumiko Suzuki
      新薬創出に向けた有機分子触媒を用いる生物活性化合物の合成 (Japanese, PDF 504KB)
      "Advanced Molecular Transformations by Organocatalysts" News Letter 2013, No. 15



Yumiko Suzuki Lab.

Sophia University
7-1, Kioicho, Chiyoda-ku, Tokyo 102-8554, Japan

TEL -81-3-3238-3089

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